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Lions @ 49ers

The San Francisco 49ers (0-1) play their second game in a row against NFC North opposition, this time the Detroit Lions (0-1). Jimmy Garoppolo previously worked alongside Lions head coach Matt Patricia in New England, but whose side will prevail?

Regular Season

Preseason

Season 2020

Season 2019

Season 2018

Season 2017

Season 2016

NFL Network