A fixture that usually has European connatations attached to it, but for both Tottenham and Manchester United, they'll be just desperate for a break from the drama - starting with three points.
Both sides find themselves with very little to play for in the wrong half of the table, with only their Europa League exploits keeping their season alive.
Spurs haven't won a home game in the league since November as the pressure continues to mount on boss Ange Postecoglou, but it could be the ideal time to face a Man United team whose struggles have continued under Ruben Amorim.
Here's what you need to know about Tottenham and Manchester United ahead of their match.
Manchester United hold the edge in this fixture, having won 96 times in 203 clashes.

(Sources: Injuries , suspensions )
(via tottenhamhotspur.com )
"I have said before I have respect for all managers because I know how tough it is. I’m sure if you ask Ruben he would just say that he is doing what he was brought in to do.
"Obviously, they have scouted and identified him, the way he plays and goes about his business. You don’t just make these appointments because you like the look of someone. You do actually a lot of work and you bring him in with a purpose.
"If anybody believes anything can change significantly in a short space of time then you are living in an alternative universe that is not based in reality. I’m sure, and who am I to advise anybody, if Man United stuck with Ruben for the next two years, they would see progress, absolutely, because that is how long it takes.
"If anybody can show me somebody who has done it quicker without significant investment, by all means put it across my desk and I will follow that blueprint. I have only spoken to Ruben for maybe 30 seconds at a game, I’m sure he is going, ‘I’m going to do what I was brought in to do', and that is what he should do."
(via Manchester Evening News )
"I’m a huge fan of Ange Postecoglou, of course I’m from a different culture, I’m Portuguese and all the Portuguese coaches can adapt, The simple thing is I use one system in the moment because I believe if you work on that system you can play in different systems at the same time, so that is the idea.
"But we are not winning games and I can understand the connection between me and Ange. We have the same problems. In my opinion, with all due respect, I am in a bigger club with bigger pressure so I understand the pressure and I think it’s important for the coach to follow all of these principles."
Two teams who are desperate for a win, but likely to cancel each other out.
Prediction: Tottenham 1-1 Manchester United