It's been a long time since Olympiacos and West Ham United last faced off.
The teams last met in official competition way back in the 1965-66 Cup Winners' Cup last 16, with West Ham winning 6-2 on aggregate.
They renew hostilities nearly 60 years later in the Europa League, where they make up half of Group A. The Hammers lead the group after winning both of their matches so far, with Olympiacos in third with a loss and a draw to their name.
The Greek side will now hope that playing on home soil against the group leaders will help reverse their fortunes.
Here's how you can watch.
For broadcast details in your country, consult UEFA.com.
Thursday's match will be played at the Karaiskakis Stadium, home of Olympiacos.