It was one of the biggest shocks of 2020 when Vasiliy Lomachenko lost his lightweight crown to Teofimo Lopez.
Desperate to return to the top following last year's setback, Lomachenko faces former world champion Richard Commey as he aims to finish 2021 in style following June's win against Masayoshi Nakatani.
Can Lomachenko send out a message to the division with an impressive win or will the tough Ghanaian ruin Lomachenko's dreams?
Here's everything you need to know.
The event takes place on Dec 11th. Vasiliy Lomachenko and Richard Commey are expected to make their ringwalks around 11pm ET (4am GMT). But those depend on the length on the undercard fights.
The fight can be seen be streamed on ESPN in the US. In the United Kingdom, it can be seen on Sky Sports.
The fight will be held at the world famous Madison Square Garden in New York City.
Nationality: Ukranian
Born: February 17, 1988
Height: 5ft 7ins
Reach: 65 inches
Total Fights: 17
Record: 15-2 with 11 knockouts
Nationality: Ghanaian
Born: March 10, 1987
Height: 5ft 8ins
Reach: 71 inches
Total Fights: 33
Record: 30-3 with 27 knockouts