NFL 2025 Week 4 schedule: Key matchups, kickoff dates and times, and how to watch

The first three weeks of the NFL season have set a high bar, and Week 4 looks ready to deliver more of the same nonstop excitement.

Here’s a look at the key matchups and the full schedule for the upcoming slate of games.

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Key matchups in Week 4

Every Week 4 game involves interesting storylines, but two stand out above the rest.

Minnesota Vikings vs Pittsburgh Steelers

• Date: Sunday, September 28
• Kick-off:  2:30pm BST / 9:30am ET / 6:30am PT

Dublin’s first-ever NFL game earns a spot on the list not just for its historic significance but for its competitive edge.

The Vikings hold the advantage on paper, although the Steelers remain a dangerous opponent.

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With a star-studded cast that includes Justin Jefferson, Jordan Mason, T.J. Hockenson, T.J. Watt, Aaron Rodgers, and D.K. Metcalf, fans at Croke Park are set to witness one of Week 4’s marquee matchups.

Philadelphia Eagles vs Tampa Bay Buccaneers

• Date: Monday, September 8 (BST) / Sunday, September 7 (ET and PT)
• Kick-off: 6pm BST / 1am ET / 10am PT

In a battle of two undefeated teams, the reigning Super Bowl champions travel to Florida to take on the Tampa Bay Buccaneers in what promises to be a titanic showdown.

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After miraculously beating the Los Angeles Rams on the final play of their Week 3 game, Jalen Hurts and Saquon Barkley will be keen to reassert their dominance.

The Bucs, led by red-hot QB Baker Mayfield, will be eager to get one over on their NFC rivals despite suffering numerous key injuries.

Week 4 Full Schedule